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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '485fe07ba307a4223c0fe575c3641058a9c80af91e08bb1b6ab4b17085c00b10' 
  AND token = 'vYj3Tx4kysIx1Ba6DPnS2FcY0NhGwqOV7u7FMEmY+yM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}