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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64d9beb03ab644bdd80b6611e34ecbac4d30948297f1aec117442797c0c867b6' 
  AND token = 'tG7Bwj3VWGSA6d0H1VIoGCv998p7A/AxJ8X2pPLuNY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}