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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9afcf53e9a2ba6301ddfc0a676aad1a07b64b6563c1f4c9386e73b254856635' 
  AND token = 'M1F/vJQCqCWd9OcgG3oA8+6e2qdWJoolBUGnIqXoQtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}