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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c6c95769e4b0e7fb0e9c278e18991235d67f59a43dec87c080e93d8fc4fc6b2' 
  AND token = 'JgW+mTnXneUopwccBVocXDDnIDY18ISrqYv9kbiU6EQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}