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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c24f4dd64e4b7c20bd2c48b5ded31f7fe80673fae4f6498cfddca969143e5e3a' 
  AND token = 'LoKkrfCXaOW2aPNPjx0RRCelllrhnFAwCT17mQcBnWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}