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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '890b06870360e68e1d11b11c448ab8d8f900d1e0f27018d6a2ad60be01c0f6ff' 
  AND token = 'HYPKVvyHMZVaENekC2C3P7lsmKjGwe1jS4w87sF6SbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}