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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4adc2cc8a7eae81e75b037a60cab1e67aaa948ac173a64d35cdd63b093369950' 
  AND token = '8HTMCSimjuMPdBZxQRzVKfHSCc+nKbOB/Iqb1N8JXig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}