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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb3bcc6e0e70bd231a1d956278bd479740df3dd6951517f07c20729ec83026bc' 
  AND token = 'iXt5Jids2dApLDS4LqH9IOUbku/CUSljD1iS9QLFdK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}