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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52ebf7bc72c5ea07dc942a2a3135b9ac41981aa1decc4903466e686d352c848b' 
  AND token = 'AJUGv/a81ziefZbcfckS2A3smT/GbN4FpaNMuliLc68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}