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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b6e93aed069580d0f8c99fc6f0ab5ba3afa563764c7168545117e077d0d5542' 
  AND token = 'DNVt++4swL34IPfZq1+JcnLGS8FUM8TT+k9BOo4mM5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}