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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '287f17c57e89b31cb85da633504c79bb8b40e17080dad644d25398025c1d58b7' 
  AND token = 'm2R61U/+n+4yZzeQUGAsmjIh+8726st0iLkPCYg7wT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}