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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46d1e3b7efdaf8c662a66fd003543a166f04c6a50ec38d3f4dd238a075f9d4d2' 
  AND token = 'VviLRq60qGHC0C0mW6ZQ2c0zj1Qqm2ddHO6V6cr38dI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}