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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a159cacdf58d93dac8a29db2a41f57c7fcf7dddd97948a687f9f39e2448cf72' 
  AND token = 'mCHrV94IdbMZEYG7YHMjqpDWzmqkR1FdUbEQ4f3kz3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}