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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8014a304aadf7e78f64cfcba40ea5c4af27f23e74e4e454a68b3fa80a4fde185' 
  AND token = 'SQfNqfIhNVA+Fx8LGe7Pu6CE0cdVT85dUrKk5UmLKTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}