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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2860c505a3a3b6ecfff7e4ee9f8032a2b7f60f44c4ef6acc3df41fd9fb18e123' 
  AND token = 'mDN54SKSsQrH6YCE0Z66G/i1DYMChZTz9XvvFLVDhlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}