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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1fc4c6916396cadeb53cd6674fed1a35a2f3127fd380854d85e746ca2b49a8d' 
  AND token = 'vhsad4MPtjmo53HgcICJ/16+0+qh5tqei4KicpD600Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}