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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a9bd3c5dd58412167363d7b8de5a1a1adac92f5ea1771f9a8589813c2066dac' 
  AND token = 'wuN1xA98caUQ9Q1NCfQ2kncYZNiweVqr6i2j62PGZDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}