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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ec14afffaf69a203fa45e08b5a5b77b681bc5ee4f52cc5de8301bf629037994' 
  AND token = 'UJ1IYUkTLIGfcDjzZkVPA0GEVD5e4aIQHZy/kz966Qg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}