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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8e236163adba1ed683b8a97d0d76721bbd1751d88e807816beaa742f9efefe9' 
  AND token = 'MLh4yKv/tVXjk6rVhIFGbTo7xBPlUYpXEFky4WsqJxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}