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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7a00e316037ee22ad38bcb41561f3e72311263a396b9f668e4e6016260def1e' 
  AND token = '+c4tC5OMYyd4ljwIkeJ9cRgn59c3YAckwjzlXwC4JZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}