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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '94cd0c3c4fa82a574dd78bfcbfac4abd1c00b32a825dc10c40870a8f61c2d07a' 
  AND token = '1+ltO5eJh3aR4Zlb22mAqAVp3R99YPeITi+s8ze4VVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}