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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4dd609a0d765fb3d9cb97808d6865711503364f7543c007a630bbd62f055611' 
  AND token = '3PM3gY1jJcjo6Ltxzzgf8XpBEVRpmf/0BNNcOnULSNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}