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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45fd900730b855de434f1d5c0e8e44f6dd706e84f1cd99033dd586b194bd572d' 
  AND token = 'EZwC6AOvUs8nuQMn6Rcp7ndTIYx7ZzHMeeetjtjosLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}