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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb2e8fd48426506c12becd2577664aef45d30db47e7e2f6f89e4a3745286a730' 
  AND token = 'cF4VcXoXvCJR1xpT8A/Y64F2+jxKa45HruR2CzLk3fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}