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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38eddafb1ab9818212ac0a298257a8748813017538c01de546babb10256f400c' 
  AND token = 'l3N2VOnV/ZmLRZ3/12Tlo3xk8f3JKPxuwoCiPhLgcRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}