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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b5745141f7d50931895a1f1c8fda99042f8a971be90a3220cee6cd465d87e60' 
  AND token = 'yoGQA9Bk5O2mrwx8qmIqB2RFi7FTM6d78SJrur7DAbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}