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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8382e388503ab151dc45404abdd38814a345f133fa3a13d052625a4a66264298' 
  AND token = 'aIuwiPAAHZqiWsQhsWAP7IF/u8Bz5rWW8nC/jEB5/SE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}