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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a7ed022580bb45ba2015d30f2ca7e52109de4d3ff7155650d98993ec0f99a38' 
  AND token = 'DRGN4XZmJEBRa69/w4VpZ87Vb17RgLHtfZiUVSU4Ku4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}