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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5d1241839af5f4a9f536ba15ab4122ecadb95a557435509c167c4e48e505e00' 
  AND token = '57Xt2XPAQvo4dGoFpxOE+wZ3iG2HVKey4g8SJQGKh6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}