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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e1469da3fb543a610ea84d543814b6f443622508f7b232804bfcc64d35252a2' 
  AND token = 'x5f7WnUEpXWy6atcMPtK20qyFTPav4BAfj83bxTjL+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}