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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c45db33de2f2aba78c15fd6daed565fe7fe1507c2b4a2139f4b6878723cadcb' 
  AND token = 'mF5Qv9sGID+I+xU20uZuA8C8olZBJIhs5U6iHgxIJy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}