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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6ef41fec55cfd14571635d530645f258f16daa8c8c1fc3043d3043573bd4baf' 
  AND token = 'OzilKMw5VItMR6K7//Uot8g57qPbra7p7KuOBMQp4yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}