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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3765370d80b260eccfecd41f49e798104ab672cedc0a4e52f7f2e04f4e53d7cd' 
  AND token = 'rGcD6mLg9OIVgs+05rtxrN1QM9qiEudAGJN+uqFVZCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}