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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59a94a54491df45af12d92e6174c10eec86dde4d60496d7c187c1309a0d8a68b' 
  AND token = 'JFhXL15BReiy8QCmuJ0IpDudXGT9+8WwXMuLI5ksgAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}