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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '666ac5776bbd9f74e080d63b4621a5c0ccc5fe7f79e3a2b11adb22f1cea2b99d' 
  AND token = 'JrFPsvx+mGorKVT+QjvwLyRakjzSaay9e71RLLAoJr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}