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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5d6a994bfd595656597e250dc0e5bc2e15b09b0dd589e0139704f9ca2700d25' 
  AND token = 'xB+JD31tnkCGVmrvJnOzNqP8HRjCj2BwrFqc3+z00ZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}