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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f20bdcb49e5782962af3507bc13e49f2c3062f049a947d5c55fe50d150fd78f' 
  AND token = 'sYXD0Hu02yO3TOVdhHHNzRdsIqgv85/JtEhznsjY4G0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}