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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d612e9e39eb52df74d5fa520477a45ea4864c1332b73ef63fb91b66e57e9c8b' 
  AND token = 'IosD3+2EYrDiqWLkDp97rkf7PQRMv5KGjxbe09v0kPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}