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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0795b6e1619c8bac487f61760e5eb506b51510b32dd0c864114af01aa40d8e09' 
  AND token = 'RuXjB2/Si5ElDtETOryBgq+958AU5pK+nDNwjHz7Qqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}