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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c643a36b02f20632145a0f536e9bd41c000c18057858b49f0413ba90fc8b705' 
  AND token = 'C8dsbHL28qiqfW/O2bSn6e+LOaB70HkRVea3MBmqqes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}