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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10378ead631a2e25495e582b5e299853e909e7b5812233abd9da86df47fd80dc' 
  AND token = 'd4xz0Q+0B7BXcx1gdK8U0RBjtpzqWCW5NeL+pS3S7Us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00068

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}