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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73106bbc8da8bc5f8f88dc48da17229a425a4416bf6a6c65aa238625fffacbe8' 
  AND token = 'BfKzHAZ0/6FsyQ3cwqXkArAeb2jCuW6IUgae7Z7CtLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}