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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '606b8bf515e6ac39e69db2511b5b154a431e1d6934da96667826812ba5d2f4f2' 
  AND token = 'UsHAsKQQujN3z2Eneh2wHAUhwQZOe+3py8SOoxnHAgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}