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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59bc164ef76bf294ed150c32961b8147e6396393aaeeecb603c01fb2b6bac049' 
  AND token = 'Mbc2FH7Geds93N9NZHyrRIgurQzwwxHPchvJ2dhJzoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}