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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aede4004ba118f94218f1f50f2542df2c0a3b0b46d1d0b05a01b8aacb2f35fff' 
  AND token = 'bs+ySgCGXCdb2GhV8H/3NQ5+5f69rvrG21zrBMuM2Uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}