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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65f442aee20eaffd1e7d744719fd98ffe0b5bb0fa49f92342a3a9a2a1aac2d22' 
  AND token = '5QfZUZGBGaXIIJNQktDsXgzrBxWUGWj9LI7UXYVDrVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}