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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42b86284c36341286120e8c78c08d8393372a8337d9dde7b9007185bae517f45' 
  AND token = 'yEunWgpGii3cqN0zddeYuxaa6HNPdBJF31GCenTYlnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}