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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1abe71ab81623088833d278ae4c469b97e0ea31d78c4a2f3b5141ab8758dd569' 
  AND token = 'vlwjk8uO79zdasFPxMa+PLGObT/644myaolC23ctDcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}