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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e95989588948e473804edb5f9f039019c849fbd2c79b21e431eb3333e0cce86' 
  AND token = 'QbMmAEp5F6ypBiZOzBUefX6mfmWvdC42DHw8sBhLGkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}