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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f6cfad2c2232dc8a8646fa362dfdf25fb454f4a7d16c38ecd3b3e598345854f' 
  AND token = 'ryk77oP89eK0hlin1m9Btf3e4Z19b0Iat5m0ynHwPTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}